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Registro Completo |
Biblioteca(s): |
Embrapa Agroenergia. |
Data corrente: |
04/12/2013 |
Data da última atualização: |
21/09/2017 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
NUNES, R. L.; SANTOS, L. L. dos; BASTIANETTO, E.; OLIVEIRA, D. A. A. de; BRASIL, B. dos S. A. F. |
Afiliação: |
Ronaldo Luiz Nunes, UFMG; Livia Loiola dos Santos, UFMG; Eduardo Bastianetto, UFMG; Denise Aparecida Andrade de Oliveira, UFMG; BRUNO DOS SANTOS ALVES FIGUEIREDO BRASIL, CNPAE. |
Título: |
Frequency of benzimidazole resistance in Haemonchus contortus populations isolated from buffalo, goat and sheep herds. |
Ano de publicação: |
2013 |
Fonte/Imprenta: |
Revista Brasileira de Parasitologia Veterinária, Jaboticabal, v. 22, n. 4, p. 1-6, 2013. |
DOI: |
10.1590/S1984-29612013000400015. |
Idioma: |
Inglês |
Conteúdo: |
Anthelmintic resistance is an increasing problem that threatens livestock production worldwide. Understanding of the genetic basis of benzimidazole resistance recently allowed the development of promising molecular diagnostic tools. In this study, isolates of Haemonchus contortus obtained from goats, sheep and buffaloes raised in Brazil were screened for presence of the polymorphism Phe200Tyr in the β -tubulin 1 gene, which confers resistance to benzimidazole. The allelic frequency of the mutation conferring resistance ranged from 7% to 43%, and indicated that resistance to benzimidazole could be found in nematodes isolated from all the ruminant species surveyed. Although significant variation in the frequency of the F200Y mutation was observed between different herds or host species, no significant variation could be found in populations isolated from animals within the same herd. These findings suggest that screening of samples from a few animals has the potential to provide information about the benzimidazole resistance status of the entire herd, which would enable a considerable reduction in the costs of diagnosis for the producer. Molecular diagnosis has practical advantages, since it can guide the choice of anthelmintic drug that will be used, before its application in the herd, thus reducing the economic losses driven by anthelmintic resistance. |
Palavras-Chave: |
Benzimidazóis; Diagnóstico molecular; Polimorfismos; Resistência a drogas anti-helmíntico; Ruminantes domésticos. |
Thesagro: |
Genética. |
Categoria do assunto: |
-- |
Marc: |
LEADER 02250naa a2200253 a 4500 001 1972839 005 2017-09-21 008 2013 bl uuuu u00u1 u #d 024 7 $a10.1590/S1984-29612013000400015.$2DOI 100 1 $aNUNES, R. L. 245 $aFrequency of benzimidazole resistance in Haemonchus contortus populations isolated from buffalo, goat and sheep herds.$h[electronic resource] 260 $c2013 520 $aAnthelmintic resistance is an increasing problem that threatens livestock production worldwide. Understanding of the genetic basis of benzimidazole resistance recently allowed the development of promising molecular diagnostic tools. In this study, isolates of Haemonchus contortus obtained from goats, sheep and buffaloes raised in Brazil were screened for presence of the polymorphism Phe200Tyr in the β -tubulin 1 gene, which confers resistance to benzimidazole. The allelic frequency of the mutation conferring resistance ranged from 7% to 43%, and indicated that resistance to benzimidazole could be found in nematodes isolated from all the ruminant species surveyed. Although significant variation in the frequency of the F200Y mutation was observed between different herds or host species, no significant variation could be found in populations isolated from animals within the same herd. These findings suggest that screening of samples from a few animals has the potential to provide information about the benzimidazole resistance status of the entire herd, which would enable a considerable reduction in the costs of diagnosis for the producer. Molecular diagnosis has practical advantages, since it can guide the choice of anthelmintic drug that will be used, before its application in the herd, thus reducing the economic losses driven by anthelmintic resistance. 650 $aGenética 653 $aBenzimidazóis 653 $aDiagnóstico molecular 653 $aPolimorfismos 653 $aResistência a drogas anti-helmíntico 653 $aRuminantes domésticos 700 1 $aSANTOS, L. L. dos 700 1 $aBASTIANETTO, E. 700 1 $aOLIVEIRA, D. A. A. de 700 1 $aBRASIL, B. dos S. A. F. 773 $tRevista Brasileira de Parasitologia Veterinária, Jaboticabal$gv. 22, n. 4, p. 1-6, 2013.
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Registro original: |
Embrapa Agroenergia (CNPAE) |
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Registro Completo
Biblioteca(s): |
Embrapa Unidades Centrais. |
Data corrente: |
30/07/2007 |
Data da última atualização: |
13/04/2017 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
Nacional - B |
Autoria: |
ALVES, E. R. de A. |
Afiliação: |
ELISEU ROBERTO DE ANDRADE ALVES, DE-PR. |
Título: |
Agroenergia: novo desafio para o Brasil. |
Ano de publicação: |
2006 |
Fonte/Imprenta: |
Revista de Política Agrícola, Brasília, DF, ano 15, n. 2, p. 3, abr./jun. 2006. |
Idioma: |
Português |
Notas: |
Carta da Agricultura. Na publicação: Eliseu Alves. |
Palavras-Chave: |
Agroenergia; Plano Nacional de Agroenergia. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/62823/1/Paginas-de-pol-agr-02-2006-3.pdf
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Marc: |
LEADER 00477naa a2200145 a 4500 001 1111234 005 2017-04-13 008 2006 bl uuuu u00u1 u #d 100 1 $aALVES, E. R. de A. 245 $aAgroenergia$bnovo desafio para o Brasil. 260 $c2006 500 $aCarta da Agricultura. Na publicação: Eliseu Alves. 653 $aAgroenergia 653 $aPlano Nacional de Agroenergia 773 $tRevista de Política Agrícola, Brasília, DF, ano 15$gn. 2, p. 3, abr./jun. 2006.
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